| MOTS-c is encoded by mitochondrial genes, rather than nuclear genes like most hormones. It works through autocrine and paracrine pathways, activating the AMPK (adenosine monophosphate activated protein kinase) pathway, increasing the number of glucose transporters on the cell membrane surface, and promoting glucose uptake by cells; Simultaneously inhibiting gene synthesis related to adipocytes and reducing lipid droplet deposition; It can also increase the activation of brown fat with faster metabolism, reduce the accumulation of white fat with slower metabolism, and enhance lipid metabolism |
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